The Hitachi 0F12450 hard drives I have a server class drives. I have three HP Z400 PC's one with six drives in it and the others with four drives each and they work just fine. One PC is running Linux RAID. Two are Plex servers and are running FreeNAS in a fault tolerant ZFS2 RAID configuration. The one with six drives shows up with 16.4 TB of storage (currently 9.4 TB used). That being said, if I remember right the RAID screens on boot shows the 3 TB drives but the BIOS only showed 728 gig in SATA mode. I am pretty sure they will work as long as the RAID controller can see them as 3TB.